{"id":902,"date":"2023-11-16T15:50:31","date_gmt":"2023-11-16T15:50:31","guid":{"rendered":"https:\/\/premieralternativemeds.com\/?post_type=product&#038;p=902"},"modified":"2026-06-24T19:22:41","modified_gmt":"2026-06-24T19:22:41","slug":"premier-liposomal-glutathione","status":"publish","type":"product","link":"https:\/\/premieralternativemeds.com\/?product=premier-liposomal-glutathione","title":{"rendered":"Premier Liposomal Glutathione"},"content":{"rendered":"<div class=\"product attribute overview\">\n<h3 class=\"value\"><strong>\u2022 Supports Healthy Immune System Function<\/strong><br \/>\n<strong>\u2022 Supports the Liver\u2019s Natural Detoxification Processes<\/strong><br \/>\n<strong>\u2022 Neutralizes Free Radicals<\/strong><\/h3>\n<p>&nbsp;<\/p>\n<\/div>\n<div class=\"product info detailed collateral-container\">\n<div class=\"product data items style1 stacked-tabs\" role=\"tablist\">\n<div id=\"description\" class=\"data item content\" role=\"tabpanel\" data-role=\"content\" aria-labelledby=\"tab-label-description\" aria-hidden=\"false\">\n<div class=\"product attribute description\">\n<div class=\"value\">\n<p>Glutathione is the master antioxidant in the body and is heavily concentrated in tissues such as the liver, spleen and heart.<br \/>\nTherefore, it plays a crucial role in immune function, detoxification capacity and protection against oxidative stress.<br \/>\nThe L-Glutathione formulation is preformed, reduced glutathione (GSH) and provides a 250 mg dose in a one-capsule serving.<\/p>\n<p><strong>Overview<\/strong><br \/>\nModern lifestyle habits like poor dietary choices, lack of sleep, abundance of stress, exposure to chemicals and exercise extremes can incur physiologic changes.<br \/>\nOur bodies were designed to handle stress, detoxify chemicals and preserve cell function, but when the burden increases, those naturally built-in systems can\u2019t keep up with demand.<br \/>\nOne of the most common physiological changes seen is the depletion of the body\u2019s most powerful antioxidant, reduced glutathione.<br \/>\nGlutathione has been termed the \u201cmaster antioxidant\u201d because of its ability to quench free radicals and protect cells from damage.<\/p>\n<p>It has long been thought that humans were unable to utilize preformed glutathione, but recent research proves otherwise.<br \/>\nSetria\u00ae, a unique tri-peptide form of glutathione, has a molecular structure that effectively increases glutathione blood levels when taken orally.<br \/>\nIt is the only supplemental glutathione backed by a human clinical trial that shows significant uptake of this critical nutrient.<\/p>\n<p><strong>Oral Supplementation and Bioavailability<\/strong><br \/>\nThe foods and supplements routinely used to boost endogenous glutathione production offer a variety of health benefits.<br \/>\nThe challenge for the practitioner becomes prioritizing what supplementation is most critical and most helpful.<br \/>\nDepending on a patient\u2019s genetics, health status and environmental exposures, even the best efforts to provide precursor molecules and cofactors may not effectively optimize glutathione production.<br \/>\nThis is because genetic polymorphisms or health challenges can alter enzymatic function in ways that hinder glutathione production or glutathione metabolism, despite excellent nutrient intake.<\/p>\n<p>According to research, supplementing with Setria\u00ae glutathione at doses of 250 mg and 1,000 mg a day for six months increased glutathione levels in whole blood, erythrocytes and buccal cells.<br \/>\nThis was the first long-term, randomized, placebo-controlled trial of oral glutathione supplementation.<\/p>\n<p><strong>L-Glutathione and Detoxification<\/strong><br \/>\nBecause of glutathione\u2019s central role in detoxification, about 25% of all glutathione resides in the liver.<br \/>\nGlutathione is more than simply an electron donor; it plays an important role in protecting living cells from toxicity by detoxifying reactive intermediates via enzymatic conjugation.<br \/>\nEnzymatic conjugation, catalyzed by the enzyme glutathione-S-transferase, occurs in Phase II liver detoxification and in gastrointestinal mucosal secretions.<br \/>\nGlutathione conjugation provides a mechanism to neutralize reactive toxins before they damage body tissues.<\/p>\n<p>Glutathione can also function as a detoxifying agent within the intestinal lumen, catching harmful toxins before they enter the body and create the necessity for liver detoxification.<br \/>\nGlutathione sources in the intestinal mucosa include intracellular synthesis, biliary supply and dietary intake.<br \/>\nThe intestinal lumen receives a large quantity of hepatic GSH from biliary secretion.<br \/>\nStudies of oral GSH supplementation have shown that the enhancement of intestinal mucosal GSH levels by oral GSH supplementation under conditions in which intracellular GSH status is compromised can restore tissue GSH and promote ROS metabolism.<br \/>\nThus, orally administered GSH may act as backup for GSH-deficient tissue.<\/p>\n<p><strong>L-Glutathione and Immune Health<\/strong><br \/>\nIt is well known that the gastrointestinal cells, the mitochondria and the efficiency of immune cell function are three major factors in immune function.<br \/>\nGlutathione happens to play a role in all three elements.<br \/>\nWhen small intestinal mucosa atrophies, it causes an increase in epithelial permeability and compromised tight junctions, which can lead to translocation of bacteria.<br \/>\nThis translocation of bacteria is implicated in immune activation and autoimmunity.<br \/>\nStudies have shown that this epithelial damage is in part due to the inability to mitigate reactive oxygen species (ROS).<\/p>\n<p>The most commonly discussed role of glutathione is in the protection of the mitochondria from free radical damage during the process of ATP production.<br \/>\nGlutathione is the master antioxidant to quench the reacted oxygen species produced as byproducts, allowing ATP production without the damaging impact that can occur in an environment lacking adequate antioxidant capacity.<br \/>\nMitochondrial health plays a crucial role in immune function via its influence on T-cell surveillance activity, pattern recognition receptor function and ATP-dependent immune functions.<\/p>\n<p>Regarding individual immune cells, decreased glutathione levels in various cells, such as T-lymphocytes, are observed in patients with immune challenges and the decreased glutathione levels are considered to contribute to a compromised immune system.<br \/>\nThe antioxidant properties of glutathione support healthy immune system function.<br \/>\nIntracellular GSH plays a key role in the maintenance and regulation of certain immunological functions, including the activation of lymphocytes and functional activity of natural killer (NK) cells.<br \/>\nWithin three months of 1,000 mg\/day Setria\u00ae glutathione, NK cell cytotoxicity increased more than twofold from baseline.<\/p>\n<p><strong>Directions<\/strong><\/p>\n<p>1 capsule per day or as recommended by your health care professional. <strong>Does Not Contain<\/strong><br \/>\nGluten, corn, yeast, artificial colors or flavors.<\/p>\n<p><strong>Cautions:<\/strong><br \/>\nIf you are pregnant or nursing, consult your health care professional before taking this product.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<div class=\"supplement-facts\">\n<div class=\"sf-title\">\n<p>\u250c\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2510<br \/>\n\u2502 Supplement Facts                             \u2502<br \/>\n\u251c\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2524<br \/>\n\u2502 Serving Size 1 Capsule                       \u2502<br \/>\n\u2502 Servings Per Container 60                    \u2502<br \/>\n\u251c\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2524<br \/>\n\u2502 Amount Per                         % Daily   \u2502<br \/>\n\u2502 Serving                            Value     \u2502<br \/>\n\u251c\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2524<br \/>\n\u2502 L-Glutathione (Reduced)             250 mg   \u2502<br \/>\n\u2502 (Setria\u00ae)                                *   \u2502<br \/>\n\u251c\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2588\u2524<br \/>\n\u2502 * Daily Value not established.               \u2502<br \/>\n\u2514\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2518<\/p>\n<p>Other Ingredients: Hypromellose (Natural Vegetable Capsule), Microcrystalline Cellulose, Silicon Dioxide and Magnesium Stearate.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<div class=\"product attribute overview\">\n<div class=\"value\">Bioavailable Antioxidant and Detox Support<\/div>\n<\/div>\n<div class=\"product info detailed collateral-container\">\n<div class=\"product data items style1 stacked-tabs\" role=\"tablist\">\n<div id=\"description\" class=\"data item content\" role=\"tabpanel\" data-role=\"content\" aria-labelledby=\"tab-label-description\" aria-hidden=\"false\">\n<div class=\"product attribute description\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"featured_media":1429,"comment_status":"open","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":""},"product_brand":[],"product_cat":[25],"product_tag":[],"class_list":["post-902","product","type-product","status-publish","has-post-thumbnail","product_cat-supplement","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=\/wp\/v2\/product\/902","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=902"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=\/wp\/v2\/media\/1429"}],"wp:attachment":[{"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=902"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=902"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=902"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/premieralternativemeds.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=902"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}